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Presenter George Lamb and doctors Andrew Curran and Radha Modgil advise people with excessive lifestyles how to become healthier and avoid serious illness.

Fast-talking former MC Tony Kemp has been taking drugs since he was a schoolboy and can down a bottle of brandy like water. He can easily spend his whole week's wages on a drugs-and-booze-fuelled weekend binge and the high-fat fast-food diet that accompanies it, including fry-ups, kebabs, burgers and pizzas and a 20-a-day cigarette habit.

Tony's fiancee Nicola has particular cause for concern about the price they both might be paying for Tony's high-octane partying. The couple have been trying for a baby for some time and, as Nicola is already a mum, she's starting to suspect any fertility problems may be Tony's.

The medical tests Tony undergoes for his living autopsy bring some uncomfortable results, and a re-emersion in the MC scene tests his new-found resolve to cut down the partying to the limit.