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Half a century ago CP Snow announced there were two cultures in the west - science and the arts. Entrepreneur and digital champion Martha Lane Fox is a passionate believer that science and arts can work together - and are already doing so. She talks to visionary architect Charles Jencks, who has created a garden that celebrates the latest discoveries in cosmology, meets experimental novelist David Mitchell, author of Cloud Atlas, explores the extraordinary creative possibilities of virtual reality, and tracks down her hero IT pioneer and art lover Dame Stephanie Shirley.