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In the first episode we meet three people who share one thing - the hope of seeing a life beyond their cancer. In north Wales, Sally, a mother of five, is hoping that a stem cell transplant will finally end her relationship with a disease she has lived with for ten years. With news that a perfect match has been found, it is possible she may finally be cancer-free. But with her body exhausted from years of treatment, it is a procedure that brings huge risk.

In Leeds we meet Dominic in the consulting room as he learns that he is one of the very few men in the country to be diagnosed with breast cancer. A straight-talking Yorkshireman, Dominic spends much of his time with his prized pigeons. As he waits for his mastectomy, it is his pigeons that occupy his mind and not his cancer.

In London, Yvette, a belly dance teacher and performer, faces a critical decision as her breast cancer, which she has lived with for 20 years, begins to spread. In the hope of halting this, Yvette is offered the chance to be at the forefront of medical science by joining a clinical trial. But it is a leap in the dark, and she waits anxiously to discover whether these new drugs might work.