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There are few living Scottish artists whose work packs quite the same emotional punch as Peter Howson. Richard Holloway swaps the radio studio for the art studio, visiting the internationally renowned painter at his place of work to explore some of the big themes his work deals with, including prophecy, religious iconography, masculinity, and depression.

The idea of Big Brother watching over us is not a new idea, but it's perhaps taken on a new dimension in the digital age. Dr Tom Chatfield, author and tech philosopher, and Dr Eric Stoddart, Lecturer in the School of Divinity at the University of St Andrews, look at the impact that state surveillance of our private communications can have on our society and our notions of freedom.

Cryogenics, implanted computer chips, cyborgs - is this the future for the human race? Mark O'Connell discusses Transhumanism, the branch of thought that believes the human race can evolve beyond its current physical and mental limitations; the subject of his latest book, To Be A Machine.

Richard speaks to 22 year old transgender man Luke Murphy and his hero and former Sunday School teacher Anne McMahon, about their truly remarkable and inspiring friendship.