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Melvyn Bragg and guests discuss how our increased knowledge of the functioning of the brain and the mechanisms of memory in the 20th century has changed our feelings about our own natures, and our approach to the behaviour and treatment of others.Many questions have been thrown up this century by our growing knowledge about how the brain and the mind function. How easy is it to establish the relationship between the two, and what light can this relationship throw on our understanding of our own and others natures? With Steven Rose, Professor of Biology and Director of the Brain and Behaviour Research Group, Open University, Dan Robinson, Distinguished Research Professor, Georgetown University and visiting lecturer in Philosophy and Senior Member of Linacre College, Oxford University.