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When Ami's young son Jivan was diagnosed with Wiskott-Aldrich Syndrome, a rare immune deficiency disease, she decided to give birth to another child, a Saviour Sibling, in order to save Jivan. Simon however, a biochemist, believes that a child should never be created for their genetic material, and that there should be laws to prevent this happening. The film poses the question: is it okay to have one child to save another?

The film features representatives of different faiths and religions explaining their perspective on having a saviour sibling.