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Doctors say a strain of drug-resistant gonorrhoea is spreading in the north of England.
The sexually transmitted infection can threaten fertility and unborn children.
The strain in this outbreak is able to shrug off the antibiotic azithromycin, which is normally used alongside another drug, ceftriaxone.
President of the British Association of Sexual Health and HIV, Dr Jan Clarke, told the Victoria Derbyshire programme that the difficulties in treating the infection were "extremely worrying".