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Home Office doctors gave the go-ahead for experimental drug trials on children at two schools in the 1960s, National Archives files show.
Parents were not consulted and the issue of consent was left to managers.
At Richmond Hill Approved School in North Yorkshire, housing pupils aged 15 and older, the most disruptive boys were given an anticonvulsant drug to see if it would control behaviour.
The trial of a sedative on girls at a school near Leeds did not proceed.
The 麻豆官网首页入口's Sanchia Berg reports.