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Mass protests break out against President Nicolas Maduro, while the US and several other foreign powers back opposition leader Juan Guaido. We get the latest from our South America business correspondent Daniel Gallas. We hear why bringing down the high price of America's prescription drugs isn't that easy in our report from West Virginia. And in Davos we speak to South African president Cyril Ramaphosa about his land reform plans.
Fergus Nicoll is joined throughout the programme by Jodi Schneider, Senior International Editor at Bloomberg in Hong Kong, and Professor Peter Morici of the University of Maryland, from Washington DC.

(Picture: A rally against President Maduro. Credit: Marcelo Perez Del Carpio/Anadolu Agency/Getty Images)