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FRONTIERS
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Frontiers explores new ideas in science, meeting the researchers who see the world through fresh eyes and challenge existing theories - as well as hearing from their critics. Many such developments create new ethical and moral questions and Frontiers is not afraid to consider these.
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Children's Medicines
Many of the medicines that children take have never been properly tested on them to make sure they are safe and effective.
Doctors often have to make do with drugs designed for adults and just scale down the dose.
This can lead to dosing errors, and adverse events can occur as children鈥檚 bodies handle some medicines differently to adults.听
Graham Easton shows how new European legislation is about to change this.
Children are at last finding their voice in the corridors of big pharma, and any medicine that could benefit children will have to be properly tested and designed with children in mind.
The UK government has spent 拢20 million on the Medicines for Children Research Network to help researchers and drug companies meet the challenge of trialling medicines in children.
Graham Easton reveals why medicines for children lag behind adults, and looks at the practical and ethical challenges that the trials pose.
But ensuring the medicines are safe and effective is just part of the challenge. Formulation scientists are also having to get to grips with the tastes and preferences of babies and children.
Graham talks to a group of chatty child ambassadors, recruited by the network to give children a voice in the running of the trials.
It鈥檚 hoped that these clinical trials will dramatically improve the quality of medicines for children and revolutionise our understanding of child health.
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